The Growing Need for Treatment Options in Uncontrolled Gout
There is a disparity between the number of clinically appropriate patients and actual utilization of therapy. Additional therapies for uncontrolled gout are needed to help address the progressive nature of the disease.1-3
Therapy Options Over the Years
There have been only 4 FDA-approved urate-lowering therapies (ULTs) for gout introduced in the last 70+ years, with no new options being approved in over 10 years.4-6
Looking to the Future of Uncontrolled Gout Treatments
Patients with uncontrolled gout who are still experiencing persistently elevated sUA levels and 2 or more gout flares each year need additional treatment options and, gout incidence is predicted to continue to grow globally.6
Global Gout Prevalence Nearly Doubles Approximately Every 30 Years6,7
100M PEOPLE
With gout expected to affect nearly 100 million people by 2050, there's a growing interest in uncontrolled gout in both publications and clinical trials.
With continued active research in uncontrolled gout, healthcare providers can be hopeful that the future treatment landscape is ever-evolving.6
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The information provided on this website is intended for healthcare professionals (HCPs) for informational and educational purposes only. It is not intended to replace the independent clinical judgment of HCPs in diagnosing or treating individual patients.
References
1. Francis-Sedlak M, et al. Rheumatol Ther. 2021;8(1):183-197. 2. Schlesinger N, et al. Nat Rev Rheumatol. 2023;19(10):640-649. 3. FitzGerald JD, et al. Arthritis Care Res (Hoboken). 2020;72(6):744-760. 4. Krystexxa Prescribing Information. Amgen. 5. Drugs.com. Probenecid alternatives compared. Accessed January 5, 2026. https://www.drugs.com/compare/probenecid 6. Punzi L, et al. Clin Exp Rheumatol. 2025;43:799-808. 7. GBD 2024 Gout Collaborators. Lancet Rheumatol. 2024;6(8):e507-e517.